医院長がこれまで関わった論文の一覧です。
臨床の専門は産婦人科（特に周産期）ですが、大学院時代は免疫に関わる基礎研究をやっていました。

産婦人科関連の論文

• Effectiveness of self-sampling human papillomavirus test on precancer detection and screening uptake in Japan: The ACCESS randomized controlled trial. Fujita M, Nagashima K, Shimazu M, Suzuki M, Tauchi I, Sakuma M, Yamamoto S, Hanaoka H, Shozu M, Tsuruoka N, Kasai T, Hata A.Int J Cancer. 2024 Apr 22. doi: 10.1002/ijc.34970. Online ahead of print.PMID: 38648390
• Acceptability of self-sampling human papillomavirus test for cervical cancer screening in Japan: A questionnaire survey in the ACCESS trial. Fujita M, Nagashima K, Shimazu M, Suzuki M, Tauchi I, Sakuma M, Yamamoto S, Hanaoka H, Shozu M, Tsuruoka N, Kasai T, Hata A.PLoS One. 2023 Jun 8;18(6):e0286909. doi: 10.1371/journal.pone.0286909. eCollection 2023.PMID: 37289798 
• Implementation of a self-sampling HPV test for non-responders to cervical cancer screening in Japan: secondary analysis of the ACCESS trial. Fujita M, Nagashima K, Shimazu M, Suzuki M, Tauchi I, Sakuma M, Yamamoto S, Hanaoka H, Shozu M, Tsuruoka N, Kasai T, Hata A.Sci Rep. 2022 Aug 25;12(1):14531. doi: 10.1038/s41598-022-18800-w.PMID: 36008554 
• Study protocol of the ACCESS trial: a randomised trial to evaluate the effectiveness of human papillomavirus testing by self-sampling in cervical cancer screening uptake and precancer detection. Fujita M, Shimazu M, Nagashima K, Suzuki M, Tauchi I, Sakuma M, Yamamoto S, Shozu M, Hanaoka H, Tsuruoka N, Kasai T, Hata A.BMJ Open. 2022 Feb 3;12(2):e049803. doi: 10.1136/bmjopen-2021-049803.PMID: 35115348 
• Metformin potentiates the anticancer effects of cisplatin under normoxic conditions in vitro. Uehara T, Mitsuhashi A, Tsuruoka N, Shozu M.Oncol Rep. 2015 Feb;33(2):744-50. doi: 10.3892/or.2014.3611. Epub 2014 Nov 21.PMID: 25421433

免疫関連の論文

• Allergic T_H2 Response Governed by B-Cell Lymphoma 6 Function in Naturally Occurring Memory Phenotype CD4⁺ T Cells. Ogasawara T, Kohashi Y, Ikari J, Taniguchi T, Tsuruoka N, Watanabe-Takano H, Fujimura L, Sakamoto A, Hatano M, Hirata H, Fukushima Y, Fukuda T, Kurasawa K, Tatsumi K, Tokuhisa T, Arima M.Front Immunol. 2018 Apr 10;9:750. doi: 10.3389/fimmu.2018.00750. eCollection 2018.PMID: 29696026 
• Development of chronic allergic responses by dampening Bcl6-mediated suppressor activity in memory T helper 2 cells. Ogasawara T, Hatano M, Satake H, Ikari J, Taniguchi T, Tsuruoka N, Watanabe-Takano H, Fujimura L, Sakamoto A, Hirata H, Sugiyama K, Fukushima Y, Nakae S, Matsumoto K, Saito H, Fukuda T, Kurasawa K, Tatsumi K, Tokuhisa T, Arima M.Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E741-E750. doi: 10.1073/pnas.1613528114. Epub 2017 Jan 17.
• ADAR1 protein induces adenosine-targeted DNA mutations in senescent Bcl6 gene-deficient cells. Tsuruoka N, Arima M, Yoshida N, Okada S, Sakamoto A, Hatano M, Satake H, Arguni E, Wang JY, Yang JH, Nishikura K, Sekiya S, Shozu M, Tokuhisa T.J Biol Chem. 2013 Jan 11;288(2):826-36. doi: 10.1074/jbc.M112.365718. Epub 2012 Dec 3.PMID: 23209284 
• Effective collaboration between IL-4 and IL-21 on B cell activation. Saito T, Kitayama D, Sakamoto A, Tsuruoka N, Arima M, Hatano M, Miyazaki M, Tokuhisa T.Immunobiology. 2008;213(7):545-55. doi: 10.1016/j.imbio.2008.01.006. Epub 2008 Feb 20.PMID: 18656702
• Bcl6 is required for the IL-4-mediated rescue of the B cells from apoptosis induced by IL-21. Tsuruoka N, Arima M, Arguni E, Saito T, Kitayama D, Sakamoto A, Hatano M, Tokuhisa T.Immunol Lett. 2007 Jun 15;110(2):145-51. doi: 10.1016/j.imlet.2007.04.009. Epub 2007 May 22.PMID: 17532053
• JunD/AP-1 and STAT3 are the major enhancer molecules for high Bcl6 expression in germinal center B cells. Arguni E, Arima M, Tsuruoka N, Sakamoto A, Hatano M, Tokuhisa T.Int Immunol. 2006 Jul;18(7):1079-89. doi: 10.1093/intimm/dxl041. Epub 2006 May 15.PMID: 16702165
• Bcl6 is a transcriptional repressor for the IL-18 gene. Takeda N, Arima M, Tsuruoka N, Okada S, Hatano M, Sakamoto A, Kohno Y, Tokuhisa T.J Immunol. 2003 Jul 1;171(1):426-31. doi: 10.4049/jimmunol.171.1.426.PMID: 12817026